Preparation and evaluation of sulindac alginate beads

Preparation and Evaluation of Ketoprofen-loaded Calcium alginate beads

Ionotropic gelation method was used to entrap Ketoprofen (KP) into calcium alginate beads. KP is one of the non steroidal anti-inflammatory drugs (NSAIDs); it has a short half life (1.5-2 h) and deleterious side effects on GIT such as irritation and ulceration. Beads were investigated in-vitro for possible sustained drug release and in-vivo as a gastro-protective system for KP. The curing time ...

Preparation and evaluation of berberine alginate beads for stomach-specific delivery.

The purpose of this research was to prepare floating calcium alginate beads of berberine for targeting the gastric mucosa and prolonging their gastric residence time. The floating beads were prepared by suspending octodecanol and berberine in sodium alginate (SA) solution. The suspension was then dripped into a solution of calcium chloride. The hydrophobic and low-density octodecanol enhanced t...

Preparation and Characterization of Alginate and Psyllium Beads Containing Lactobacillus acidophilus

This paper describes preparation and characterization of beads of alginate and psyllium containing probiotic bacteria of Lactobacillus acidophilus DMSZ20079. Twelve different formulations containing alginate (ALG) and alginate-psyllium (ALG-PSL) were prepared using extrusion technique. The prepared beads were characterized in terms of size, morphology and surface properties, encapsulation effic...

Preparation of alginate-chitosan hybrid gel beads and adsorption of divalent metal ions.

Naturally occurring polysaccharides such as alginic acid and chitosan have been recognized as one of the most effective adsorbents to eliminating low levels of heavy metal ions from waste water stream. The present study intended to use alginic acid and chitosan simultaneously, which are expected to form a rigid matrix structure of beads due to electrostatic interaction between carboxyl groups o...

preparation and comparision of alginate beads containing lactobacillus acidophilus by cacl2 and alcl3 as crosslinker